Immunoprotective Activity of Polysaccharides from Eucommia Ulmoides on Intensive-exercise Mice

Abstract

The aim of this study is to investigate the immunoprotective effect of Eucommia Ulmoides Polysaccharide (EUP) on intensive exercise mice. EUP were isolated and its physicochemical properties were analyzed. Meanwhile, an intensive exercise model of mice was established and EUP were orally treated during exercise and some immunological parameters were measured at the end of the training session, such as thymus and spleen index, lymphocytes proliferation, natural killer (NK) cells activity. The results showed that EUP was a polysaccharide-protein conjugates and significantly increased the spleen index and activities of NK cells. In conclusion, EUP can ameliorate the exercise-induced immunosuppression.