Cold-hot Nature Distinguish of Traditional Chinese Medicinal Herbs by Discriminant Analysis of 1H-NMR Spectral Data
Abstract
“Cold-hot nature†is the key part of the theory on herb properties in traditional Chinese medicine (TCM). Traditionally, the cold-hot natures of medicinal herbs were ascertained mainly dependent on medicinal experience. Nowadays systematic methods considering the material basis from a variety of chemical substances are needed and may be reliable to differentiate cold-hot nature of various herbs. In the present study, nuclear magnetic resonance spectroscopy of proton (1H-NMR) was combined with pattern recognition techniques for cold-hot nature classification of Chinese medicinal herbs for the first time. 1H-NMR determination was carried out on 62 kinds of Chinese medicinal herbs. Canonical discriminant functions (CDF) and fisher discriminant analysis (FDA) then were applied to analyze the large 1H-NMR spectra data set obtained. The results indicated that the combination of 1H-NMR and multivariate statistical analysis may provide a more efficient means for the research and exploration of cold-hot nature of medicinal herbs.
Keywords
Chinese Medicinal Herbs, Cold-Hot Nature,1H-NMR, Discriminant Analysis
DOI
10.12783/dtbh/mshh2017/13435
10.12783/dtbh/mshh2017/13435
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