The Application Progress of MicroRNA in Cerebral Ischemia-reperfusion Injury

Abstract

Ischemia-reperfusion injury (I/R) is caused by the blood flow obstruction and is
further aggravated by restoration of the blood supply suddenly. The brain is the most sensitive organ in the human body; ischemia can cause irreversible damage to brain cells after a few minutes. Therefore, exploring the prevention and treatment of cerebral ischemia-reperfusion injury are of great significance. In the current studies, scholars have found that microRNAs are closely related to the mechanism of cerebral ischemia-reperfusion injury, and gene therapy based on microRNAs is expected to be a new method for it.