Development and Activity Evaluation of Antialcoholism and Liver Detox Jiaosu

Abstract

The antialcoholism and liver detox Jiaosu selected traditional Chinese medicine with antialcoholism effect, such as pueraria lobata, hawthorn, poria cocos as raw materials. After bioenzymatic hydrolysis, Lactobacillus rhamnosus 217-8 with high glutathione production was selected as fermentation strain. After fermentation, the Jiaosu was placed in a constant temperature and humidity environment, and the contents of flavonoids, puerarin, polyphenols and antioxidant capacity of Jiaosu were determined. The results showed that the content of puerarin was increased by 7 times, flavonoids increased by 3 times, amino acids increased by 6 times, polyphenols increased by 80mg/L, the antioxidant capacity increased by 92% of antialcoholism and liver detox Jiaosu compared with the raw material without enzymatic hydrolysis and fermentation. So we can draw the conclusion that the optimization and compatibility of radix puerariae, hawthorn, poria, through enzymatic hydrolysis and microbial transformation, not only the natural active ingredients intact and release, some of the macromolecular components can be transformed into small molecular components, which are beneficial to human absorption and metabolism, but also produce active secondary metabolites at the same time, and further improve the types and functions of active components in antialcoholism and liver detox Jiaosu. So, the antialcoholism and liver detox Jiaosu developed in this paper has an important potential in accelerating the circulation of tri-carboxylic acid and promoting the decomposition of acetaldehyde, improving the concentration of ethanol and triglyceride in the blood, and improving the anti - oxidation ability of the liver tissue.