A Flexible Microelectrode Array for Recording Signals of Culturing DRG Explants

Abstract

Owning to the advanced technology of microelectromechanical systems (MEMS), more and more precise microelectrode arrays are used to serve as neural prosthesis. Peripheral nerve injury and amputation have plagued neurosurgeons and patients. Neural interface have been served as a bridge between peripheral nerves and prosthetic limbs. In this study, to characterize the signals of culturing dorsal root ganglion (DRG) explants, a flexible electronic microelectrode arrays using SU-8 was designed to serve as neural interface to record neural signals of culturing DRG explants. The arrays are composed of thin gold electrode on a flexible material called SU-8, The materials and methods will play an important role in recording neural signals of culturing DRG explants. The goal of this study is to design an artificial limb that the amputees could control as if it was a natural extension of their own body.