Comparison of the Impact on the Extubation Between Desflurane and Sevoflurane in Obese Patients Undergoing Thyroidectomy

Chun-lu ZHANG, De-wu ZENG, Lu CHEN, Wei-kang WANG, Peng CHEN


Objective: Comparison of the impact on the extubation between desflurane and sevoflurane in obese patients undergoing thyroidectomy. Method: A total number of 60 obesity cases aging between 32~60 were selected, randomly divided into 2 groups, named Desflurane Group (30 cases) and SevofluraneGroup(30cases). Patients were required for anesthesia detection. Penehyclidine 0.5mg. Induction of anesthesia was 1ED95 rocuronium bromide 0.3 mg/kg, midazolam 2mg, propofol 2 mg/kg and sufentanil 0.5 μg/kg.The drugs facilitate tracheal intubation with nerve monitoring function and mechanical ventilation, tidal volume 8~10ml/kg, respiratory rate12/min. Maintained the anesthesia with 1.2~1.4 MAC of desflurane or sevoflurane. Stopping medication after surgery. We recorded the OAA/S scores at 5min, 10min, 20min and 30min later after extubation and Riker agitation sedation scores. SPSS 20.0 software was used to analysis results. Results: Compared with sevoflurane, desflurane has a certain clinical application advantages applying in obese patients with nerve monitoring complexity thyroidectomy, showing short recovery and extubation time obviously. But desflurane showed a higher incidence of postoperative agitation than sevoflurane.


Desflurane, Sevoflurane, Obese, Thyroid surgery, Recovery quality



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